Supporting a Breakthrough Cure for Sickle Cell Disease

Imagine living with a disease that causes excruciating pain, when every fever means a trip to the emergency room, where a stroke is a very real possibility. Children with sickle cell disease face these challenges. Today, the only cure for this chronic, inherited condition — bone marrow transplantation — is so limited that relatively few procedures are completed. But major breakthroughs are near.

The 2018 31-Day Challenge benefitted the Comprehensive Sickle Cell Center at Children’s Hospital of Philadelphia, one of the largest and most active centers of its kind in the U.S., caring for more than 1,000 patients annually. Our clinicians and researchers have pioneered advances that have dramatically improved the lives of children with sickle cell disease — and our team is on the verge of a potential new cure.

After 30 years of laboratory studies, we are now on the brink of a cutting-edge therapy to treat sickle cell disease before birth using a mother’s stem cells on the baby still in her womb. A landmark clinical trial, led by CHOP, is expected to begin soon.

Other Ways to Support CHOP

While the Comprehensive Sickle Cell Center is the designated beneficiary for the 31-Day Challenge, you can choose to support pediatric research, patient care or a specific area of the Hospital. Directed donations must be received by June 30, 2018.

Autism Research and Care

Children with autism spectrum disorders benefit from care, treatment and ongoing research by experts at CHOP.

Cancer Center

Oncologists at CHOP deliver expert treatment and develop new ways to treat cancer more safely, effectively and with fewer side effects.

Cardiac Center

Patient outcomes at the Cardiac Center are among the best in the world, placing us in the top tier of pediatric cardiac programs.

Child Life

Child Life Services at CHOP was one of the first in the nation to recognize the therapeutic value of play for hospitalized children.

Critical Care

Experienced critical care experts treat children with life-threatening illnesses and injuries in CHOP’s intensive care units.

Cystic Fibrosis

Children with cystic fibrosis receive specialized care and treatment that promotes growth and slows the progression of the disease.


The Division of Endocrinology and Diabetes provides advance treatment options for a broad range of endocrine disorders.

Fetal Diagnosis and Treatment

The Center provides care for babies with prenatally diagnosed birth defects and continues to research new ways to treat life-threatening conditions.

Integrative Health

CHOP offers a broad umbrella of integrative health programs that combine traditional and alternative medicine to treat the whole child — mind, body and soul.

Newborn/Infant Intensive Care Unit

The multidisciplinary team provides expert care for critically ill newborns and premature infants, and offers seamless access to specialty services.


Neurological disorders can affect how your child’s brain is growing and developing. At CHOP, we offer advanced treatment for all neurological conditions.

Palliative Care and Bereavement

CHOP offers psychological, social and spiritual services to support children with life-limiting illnesses and their families.

Plastic Surgery

Using the most advanced tools and techniques, plastic and reconstructive surgeons provide children with the individualized care they need.

Rehabilitative Medicine

The Center for Rehabilitative Medicine is dedicated to empowering patients and their families to optimize their quality of life.

Trisomy 21

The Trisomy 21 Program assesses the developmental, behavioral and health needs of children and adults with Down syndrome (trisomy 21).